CoCrNi alloys are a new family of high-performance alloys, which have found use in a variety of applications, including automotive, aerospace, and biomedical industries. The alloys can be manufactured by different processes, and they offer excellent properties such as high strength, good ductility, biocompatibility, and corrosion resistance. This article discusses the manufacturing route, phase evolution, and mechanical properties of medium-entropy CrCoNi-based alloys processed by means of powder-metallurgy techniques. Some of the main results obtained indicate that there is the presence of a Co–Cr–Ni solid solution and a mixture of f.c.c. and b.c.c. structures in the alloy. The microstructure is homogeneous with equiaxial grains and contains a mixture of phases due to the alloying elements. The alloy presents high mechanical strengths with good strain values. The presence of different phases, between them a Co–Cr–Ni solid solution and Co–Ni one with dissimilar crystalline structures, is the cause of the high entropy of the alloy and, consequently, of its good mechanical characteristics.