The results of research of the structure and properties of high-entropy cermets of Ti–Cr–Fe–Ni–C system prepared from the original mixture of ferrotitanium, high-carbon ferrochrome, and nickel powders, using methods of powder metallurgy (hot forging of powder preforms) and arc remelting, are presented in this article. The samples obtained by means of both technologies are subjected to subsequent annealing at temperatures of 1000, 1100 and 1200°C. As established based on the results of x-ray diffraction analysis, the phase composition of the alloy includes two disordered solid solutions with f.c.c. (predominantly) and b.c.c. structures, and carbide phases: cubic $Me$C (for hot-forged samples) and $Me_7$C$_3$ (for samples obtained by arc remelting). A significant difference in the nature of the microstructure of alloys obtained by different technologies is shown. The evaluation of the mechanical characteristics of the obtained materials shows that their hardness in the initial state is of 62 $HRC$, and the estimated values of the yield strength $\sigma_{\textrm{s}}$ obtained from the results of indentation for the materials of both manufacturing technologies is of about 3.0 GPa. Annealing and increasing its temperature leads to a certain decrease in the values of hardness and yield strength of the alloy.